Protect, then load: a brace and early walking beat a castStrong evidence
The clinical guideline's top grade goes to a brace or tape with gradually more weight through the foot. For more severe sprains, a semi-rigid brace or a below-knee cast for up to 10 days may help. In the CAST trial of 584 people with severe sprains, a 10-day below-knee cast gave faster recovery than a tubular compression bandage (ankle function 9% better at 3 months), a semi-rigid brace 8% better and a walking boot no better; by 9 months there were no differences. Four weeks in a cast delayed the return to work and sport compared with functional treatment.
NHS hospital leaflets: walk as comfort allows; a boot or crutches may be given for comfort but haven't been proven to help healing; wean off a support after 2 to 3 weeks.
Sources 8, 9, 17, 5, 6
Start gentle exercise in the first weekEmerging evidence
In 101 people with mild to moderate sprains (grade 1 or 2), an accelerated programme with exercise in week 1 gave better function at weeks 1 and 2, and more walking, than standard rest, ice, compression and elevation, with no extra re-injury (4% in each group). The guideline recommends structured exercise for range, stretching, strength and balance, in clinic and at home, and an overview of reviews found strong evidence for early mobilisation and moderate evidence for exercise.
Sources 16, 8, 10
Rest, ice, compression and elevation: standard first aid, thin evidenceMixed evidence
For the first 2 to 3 days, the NHS advises protection, rest, ice (up to 20 minutes every 2 to 3 hours), compression and elevation, and avoiding heat, alcohol and massage; then keep the ankle moving once pain doesn't stop you. A review of 11 trials (868 people) found too little evidence to judge rest, ice, compression and elevation, and the guideline says repeated ice may be used alongside exercise.
Sources 1, 15, 8
Painkillers: short-term relief, with a cautionMixed evidence
Anti-inflammatories reduce pain and swelling in the short term, but the Dutch guideline urges care because of side effects and possibly slower healing. The NHS suggests paracetamol and ibuprofen gel first, then tablets if needed. Ask a pharmacist.
Sources 10, 9, 1
Balance training and a brace cut repeat sprainsStrong evidence
Exercise-based rehab lowered re-injury over the following year in two meta-analyses (odds ratios 0.53 and 0.60), with no link between how much training people did and the benefit. In the 2BFit trial of 522 athletes, an unsupervised 8-week home balance programme cut repeat sprains from 33% to 22%: one fewer sprain for every 9 people who trained, even though only 23% completed it fully. Sessions were three a week of up to 30 minutes, ideally as a warm-up, starting once usual care had ended and sport had resumed, and progressed from standing on a flat surface, to eyes shut, to a balance board.
A brace for sport cuts repeats too: in one trial 15% re-sprained with a brace against 27% with home training alone, and lace-up braces cut ankle injuries in 1,460 school basketball players. The guideline recommends both a brace and balance training after a first sprain.
Sources 18, 19, 20, 21, 24, 25, 8
Balance training to prevent a first-ever sprain is unprovenMixed evidence
Balance training reduced sprains in sporting groups overall and in people who had sprained before, but the evidence for preventing a first sprain is inconclusive. In volleyball, a balance board programme reduced sprains only in players with a previous sprain.
Sources 23, 22, 8
Back to sport: more than timeEmerging evidence
An international consensus of 155 professionals bases the return to sport on five checks (PAASS): Pain during sport and over the next 24 hours; Ankle range, strength, endurance and power; the Athlete's confidence and feeling of stability; Sensorimotor control, meaning balance; and Sport performance: hopping, jumping, agility, sport drills and finishing a full session. In one cohort, not being able to complete jump-landing tasks 2 weeks after a first sprain predicted later chronic instability.
If recovery stalls, a physiotherapist can check how the injury happened, the bones and ligaments, and the movement and balance problems linked to an ankle that keeps giving way.
Sources 26, 28, 29
What not to rely onStrong evidence
The guideline advises against therapeutic ultrasound. An overview of reviews found too little evidence for ultrasound and conflicting evidence for acupuncture and surgery, and the Dutch guideline keeps surgery for sprains that don't respond to thorough exercise-based treatment.
Sources 8, 10, 9