Steroids, SARMs and other drugs: the harms
This is harm information, not advice on use. If you use them or are thinking about it, a GP can help, and Talk to FRANK gives confidential advice.
The lawStrong evidence
Anabolic steroids are Class C, prescription-only medicines. Having them for your own use is legal, and you can import or export them only in person. Supplying them, including giving them to friends, carries an unlimited fine or up to 14 years in prison. They're banned in tested sport.
Sources 15, 90
What the NHS listsStrong evidence
The NHS's list of harms:
- In men: reduced sperm count, infertility, shrunken testicles, erection problems, hair loss, breast development and severe acne.
- In women: facial and body hair, smaller breasts, a deeper voice, problems with periods and severe acne.
- In both: heart attack or stroke, liver or kidney problems or failure, high blood pressure, blood clots in the legs, fluid retention and high cholesterol.
- Aggression, mood swings, paranoia and, in teenagers, stunted growth.
- From shared needles: hepatitis B, hepatitis C and HIV.
Source 15
AddictionStrong evidence
The NHS: "Anabolic steroids are addictive." Stopping suddenly can bring depression, anxiety, tiredness, insomnia and loss of appetite, and the NHS says to see a GP if you think you're addicted. In a review of 18 studies, about a third of users became dependent.
Sources 15, 91
The heartEmerging evidence
In 140 experienced weightlifters, long-term steroid users' hearts pumped less well than non-users' (52% against 63% of blood pumped out with each beat), and they had more plaque in their heart arteries. In 101 long-term users, both current and former users had weak heart muscle; in a follow-up, those who stopped improved towards non-users. During a single course of steroids, blood pressure and cholesterol worsened, and returned to normal within months of stopping.
Sources 17, 32, 92, 93
DeathsEmerging evidence
Danish gym users who tested positive for steroids had about three times the death rate of other men, and Finnish championship powerlifters suspected of steroid use died about four and a half times as often over 12 years. In 20,286 male IFBB competitors from 2005 to 2020, sudden cardiac death ran at 32.83 per 100,000 athlete-years in those competing at the time, about five times as often in professionals as amateurs. That study found deaths by searching news and web reports, so it's probably an undercount, and drug use was confirmed in few cases: steroids were found in 3 of the 5 toxicology reports available.
Sources 94, 95, 31
Fertility and hormonesEmerging evidence
In 100 men followed through one course of steroids, every man had at least one harmful effect and 4 had a serious one, including heart failure. During use, 77% had a low sperm count (below 40 million); a year later, 34% still did and 11% had low testosterone. In former users, 27% had testosterone below the normal range years after stopping.
Sources 96, 97, 98
SARMs, insulin and DNPStrong evidence
No SARM is approved for human use, and UKAD says the evidence suggests they are "not safer than anabolic steroids": reports link them to liver injury, heart attack and stroke risk, and blood clots. In 41 people without diabetes who used insulin to build muscle, 57% had low blood sugar. Talk to FRANK warns that DNP (2,4-dinitrophenol), a toxic slimming drug, has caused deaths.
Sources 99, 100, 101, 102, 103
How commonEmerging evidence
Worldwide, about 6% of men and 2% of women have ever used anabolic steroids. In a survey of 235 competitive male bodybuilders, 53.6% of those not in natural competitions used performance-enhancing drugs, and in one online survey, 61 of 96 competitive bodybuilders had used steroids.
Sources 104, 19, 81
Getting helpStrong evidence
The NHS says there's "no evidence" that cycling, stacking or pyramiding steroids reduces the harms. A GP can help, and can refer you to a specially trained drugs counsellor; Talk to FRANK gives confidential advice about drugs.
Sources 15, 103