Early specialist assessment comes firstEmerging evidence
A UK review says early diagnosis and referral are essential, because the bone normally breaks down within 2 years, after which the joint can't be saved, and early treatment raises the chance of keeping the hip to 70% to 80% over 5 to 7 years. It also advises telling the teams who prescribe steroids, chemotherapy or immune treatment, so they can review them.
Source 5
Crutches ease pain, but on their own don't stop itEmerging evidence
A main aim of care without surgery is to take load off the hip, usually with crutches or a walking aid, the Royal National Orthopaedic Hospital (RNOH) says. But reviews say restricting weight on its own doesn't stop the disease getting worse, and in older studies only 22.7% of 819 hips managed without surgery had good results.
One 2026 trial in China (56 people, 96 hips, early and middle stages) found that 3 months of daily crutch walking eased pain by 3.1 points out of 10 at 90 days, and improved hip function and walking, compared with no walking aid. Whether it protects the bone in the long run isn't known.
Sources 2, 1, 20, 3, 21, 22
Exercise: keeps you moving, can't restore the blood supplyEmerging evidence
The RNOH advises exercises that strengthen the muscles around the hip, the leg and the trunk, keep the hip moving and build fitness, choosing those that put less load through the hip, such as water exercise or a stationary bike. Exercise can't restore the blood supply or reverse collapse.
In a small trial in sickle cell disease (46 people randomised, 38 analysed), physiotherapy alone did as well as core decompression plus physiotherapy at about 3 years: 86% and 82% of hips hadn't needed further surgery, and hip scores rose by 15.7 and 18.1 points. The differences weren't significant, and the trial was too small to be sure.
Sources 2, 23
Medicines: no proven way to stop collapseEmerging evidence
Painkillers ease pain but don't change the disease. Bone-strengthening drugs (bisphosphonates) didn't prevent collapse or hip replacement in two randomised trials, of alendronate (65 hips) and zoledronate (110 hips), and a review of randomised trials found the same. A German guideline says iloprost and alendronate can be tried; other drug and physical treatments, such as shockwave, magnetic field therapy and high-pressure (hyperbaric) oxygen, are still experimental.
Sources 2, 24, 25, 26, 13, 3
Core decompression and other hip-saving surgeryEmerging evidence
Core decompression drills one or more channels into the ball of the hip to relieve pressure and let new blood vessels grow, sometimes with bone graft or your own bone-marrow cells. It's for early disease, before the ball collapses, and remains the main operation at that stage; a German guideline suggests it when the dead area is under 30% of the ball.
In older studies, 63.5% of 1,206 hips had good results after core decompression, against 22.7% with care that didn't involve surgery. A meta-analysis of 32 studies (2,441 hips) found 65% success after about 4.5 years. In 10 randomised trials (530 hips), adding bone-marrow cells gave better pain relief, function and hip survival than core decompression alone, though the studies varied a lot. Afterwards you'll use a walker or crutches, and the American Academy of Orthopaedic Surgeons (AAOS) says people typically walk without them at about 3 months.
Sources 1, 16, 3, 13, 21, 27
Hip replacementStrong evidence
Once the ball has collapsed and arthritis has set in, a hip replacement relieves pain and restores function in most people, and results are now similar to those for arthritis. Across 67 reports (3,277 hips), the rate of repeat surgery fell from 17% before 1990 to 3% after. It was higher with sickle cell disease, Gaucher disease and kidney failure or a kidney transplant, and being young is the main risk for a later repeat operation. The hip replacement guide covers recovery.
Sources 1, 3, 12, 13