Strength training builds strengthStrong evidence
A Cochrane review (29 trials, 926 people, mostly children, all at high risk of bias) found resistance training increased muscle strength in the short term, though not clearly at the intermediate term. In people aged 8 to 25 at GMFCS levels I to III, progressive resistance training increased leg strength (6 trials, 232 people, moderate certainty), more with gym-based programmes. A 2019 review of reviews rates strength training as effective for strength, and in adults (6 studies, 111 people) strength rose consistently.
Sources 6, 7, 8, 27
Its effect on walking and everyday functionMixed evidence
The Cochrane review found low-quality evidence that resistance training doesn't improve gross motor function, walking speed, participation or quality of life in children. A later review of 27 trials (847 children and young people with spastic CP) found small improvements in balance, walking speed and gross motor function, with most trials at some or high risk of bias. In adults, walking speed improved in 2 of 6 studies, and NICE's committee found little or no improvement in mobility, function or participation from activity programmes.
Sources 6, 9, 27, 28
It doesn't increase spasticityStrong evidence
Strength training was once thought to make muscles stiffer and spasticity worse. Trials found no increase in spasticity.
Sources 10, 9
SafetyEmerging evidence
NICE's adult guideline committee noted that the risk of injury or other side effects wasn't increased by activities such as strength training. The Cochrane review says exercise appears to be safe, though only 55% of trials reported side effects.
Sources 28, 6
Aerobic exerciseMixed evidence
The Cochrane review found aerobic exercise may improve gross motor function a little in the short term (3 studies, 65 people, low quality), but not walking speed, and fitness didn't differ from usual care in 3 small trials. Individual trials reported fitness gains of 9% to 41% after 8 weeks to 9 months of training, with no side effects, and the 2019 review rates fitness training as effective.
Sources 6, 10, 8
Activity programmesEmerging evidence
The 2019 review rates fitness training, strength training (for strength), treadmill training and goal-directed training as effective for children. Physical activity programmes probably improve fitness, activity, mobility, taking part and quality of life, but don't seem to improve gross motor skills.
Source 8
StretchingStrong evidence
Across 18 studies (549 people) with neurological conditions, stretching changed joint range by about 2 degrees, which makes no real difference (high-quality evidence). In children with CP, evidence that stretching increases range, reduces spasticity or improves walking is limited, and longer stretches looked better than short ones. In a small trial, adding calf strengthening to stretching changed the calf muscle and tendon more than stretching alone. A UK trial of a tailored stretching programme for 334 children (SPELL) is expected to report in 2027.
Sources 11, 12, 29, 30, 31
Falls in adultsEmerging evidence
In UK GP records of 1,705 adults with CP, 15.3% had a recorded fall compared with 5.7% of matched adults, and falls recorded in GP records were about 6 times as common (30.5 compared with 6.7 per 1,000 person-years). Because these are falls that reached the GP's records, differences in recording could push the figure either way. In 17 adults who walked, those who fell took shorter strides, and in UK interviews falls and fear of falling were a problem for over half of 26 adults.
Sources 15, 32, 33
Walking over timeEmerging evidence
In 16 studies, walking declined in at least 25% of adults, earlier than in other people; the risk was higher with poorer walking to begin with, CP affecting both sides, older age and more pain or fatigue. Over 16 years, walking speed fell by 0.13 metres a second and 6-minute walk distance by 84 metres in adults with CP affecting both sides, but held in those with one side affected.
Sources 14, 26
FatigueEmerging evidence
Fatigue is common and fairly stable over the years. Adults who did more moderate to vigorous activity reported less fatigue, though that was a snapshot study. A 6-month programme of fitness training and coaching on activity and sport, tested in 57 young people aged 16 to 25, reduced fatigue during the programme and improved pain and mental health scores afterwards, but didn't increase measured daily activity.
Sources 17, 34, 35, 36
PainEmerging evidence
About 70% of adults with CP have pain (data from 1,243 adults), mostly in the legs, and more often women and people at GMFCS levels II and IV. In a review of 63 studies, medicines and surgery didn't reduce pain in trials, while an active lifestyle and sports programme did, though the evidence is low to very low quality.
Sources 16, 37
Mood and heart healthEmerging evidence
In UK GP records, adults with CP were more likely to develop depression (1.28 times) and anxiety (1.40 times) than matched adults. Across 69 studies, adults with CP more often had high blood pressure, type 2 diabetes, heart disease and stroke. In England, deaths from heart and circulation disease were about 3 times, and from lung disease about 14 times, the rates in the general population. These are observational studies.
Sources 23, 24, 25