What a plica isStrong evidence
Plicae are folds of the knee's lining (the synovium). They are left over from thin walls that divide the knee early in its development, before birth, and are only partly absorbed. There are four: above the kneecap, along its inner edge (the medial plica), below it, and rarely on the outer side. The medial plica is the one that usually causes trouble.
Sources 1, 2, 3
Most knees have oneEmerging evidence
In 3,889 knees seen at keyhole surgery in Japan, 80% had a medial plica. On MRI (magnetic resonance imaging) of 342 painful knees, 48% had one. A normal plica is thin, flexible and almost see-through: on dynamic ultrasound of 60 knees of volunteers without symptoms, 23 showed a plica, and none of them looked abnormal.
Sources 4, 5, 2, 6
When it becomes painfulEmerging evidence
A blow, a sudden increase in activity, or inflammation inside the knee can irritate the plica. It thickens, scars and loses its stretch, then rubs over the inner bump of the thigh bone or tugs on the lining, causing pain and sometimes wear of the cartilage next to it. An injury started it in 57% of 969 operated patients in a review, but only 16% of the 48 people in a Danish trial recalled one.
Sources 1, 7, 2
Who gets it, and how it feelsEmerging evidence
Mostly teenagers and young adults: the average age was 25 in the review of 969 patients and 27 in the Danish trial, and a British trial was in children and teenagers.
The main symptom is pain at one spot on the inner front of the knee. In the Danish trial, 67% also had clicking, 67% pain when sitting, 25% snapping, 25% a feeling of instability and only 8% swelling. Stairs, squatting, bending and getting up after sitting for a long time bring it on, and some people feel the knee catch.
Sources 1, 7, 3, 8, 2, 9, 10
How it's recognised, and what scans showEmerging evidence
It's a diagnosis of exclusion. Other causes of pain at the front of the knee, such as runner's knee, a meniscus tear, cartilage damage or tendon problems, are ruled out first, often with an MRI. The plica is then diagnosed from tenderness over a band on the inner edge of the kneecap, sometimes with a snap you can feel.
In a review of 7 studies (492 knees) checked against keyhole surgery, an examination test picked up 90% of painful plicae and was correctly negative in 89% of knees without one, and ultrasound did nearly as well (90% and 83%). MRI picked up 77% but wrongly flagged 42% of knees without plica syndrome. In another study, an examination method was confirmed at keyhole surgery in 44 of 48 people, and a 2026 study of 156 knees found MRI showed the plica well but classified it poorly. A scan can show a plica, but not whether it's the cause of your pain.
Sources 7, 2, 11, 12, 13
How common it is as a causeEmerging evidence
It's an uncommon cause of knee pain. In one Brazilian clinic, 63 of about 3,200 people with knee problems (2%) were thought to have it, and in one US series, 76 of nearly 2,000 keyhole examinations (4%) found a thickened plica as the only problem. Estimates range from 3 to 30%, depending on the group studied.
Sources 3, 14, 2, 7
How it usually goesMixed evidence
Many people improve with about 3 months of conservative care: 55 of 63 in one series. Results were more mixed in another, with 40% good, 20% average and 40% poor results in 136 people, and at a German surgical centre, 76 of 117 people (65%) went on to surgery after 3 months. People who stopped their exercises tended to slip back.
Sources 3, 15, 16, 7
How it differs from other front-of-knee pain
Runner's knee hurts around or behind the kneecap more widely; the Danish trial left out people with that kind of pain for this reason. Jumper's knee hurts on the tendon below the kneecap, a meniscus tear hurts on the joint line and can lock, and pes anserine pain sits lower, on the inner shin. Each has its own guide.
Source 7