What it is
Osteochondritis dissecans is a problem of the bone just under the joint cartilage. A patch of bone weakens, the bone and the cartilage over it can crack and loosen, and a piece can come free into the joint as a loose body. In the knee it is usually on the rounded ends of the thigh bone: in one population study, 64% were on the inner (medial) end and 33% on the outer end, and a few on the kneecap or the groove it runs in.
The cause isn't known. Repeated stress from sport, a disturbance in how bone forms under the growth cartilage, a reduced blood supply and genes are all proposed, and in US health records, clotting disorders were linked with it as well as sport. It has nothing to do with obsessive-compulsive disorder.
Sources 1, 2, 3, 4
Who gets it
Mostly active children and teenagers. In a US health system of over a million children, it was diagnosed in 9.5 per 100,000 aged 6 to 19 each year: 15.4 per 100,000 boys and 3.3 per 100,000 girls, more often at 12 to 19 than at 6 to 11, and never under 6. In a US county over 38 years, it peaked at ages 11 to 15. In US records from 2017 to 2024, gymnastics, volleyball and cheerleading carried the highest risk of the sports studied.
Adults get it far less often: 1.21 per 100,000 aged 20 to 45 each year, mostly men.
Sources 3, 5, 4, 6
It can be painless, and in both kneesEmerging evidence
In a Dutch population study, MRI (magnetic resonance imaging) scans of 1,910 13-year-olds found knee OCD in 1 in 174, all boys, and they were no more likely to have knee pain than other children. None of the 7 scanned again at 17 still had a lesion.
In a US population study, 7% of cases were in both knees. Of 80 children with pain in one knee, 15% had a lesion in the other knee too, and two-thirds of those later needed surgery on it.
Sources 7, 3, 8
How it's recognised
Pain and swelling, often brought on by sport, are the usual first signs, and an NHS trust leaflet describes a mild ache that gradually gets worse. Later, a loose piece can make the knee catch, lock or give way. The American Academy of Orthopaedic Surgeons (AAOS) guideline lists the symptoms that should prompt imaging: pain, swelling, locking, catching, popping or giving way, with tenderness, fluid in the knee, lost movement or grating.
Loose pieces have other causes too. A dislocated kneecap can knock off a piece of bone and cartilage, and arthritis can produce loose pieces in older adults; both have their own guides. This one is about OCD.
Sources 1, 9, 10
X-rays first, then MRIStrong evidence
X-rays come first, including a 'tunnel' view that shows the back of the rounded ends of the thigh bone; early or stable lesions can be missed on them. MRI then shows whether the cartilage is intact or cracked, whether fluid has got behind the piece, whether it has come loose, and how big the lesion is. The AAOS guideline supports MRI for this with strong evidence.
Sources 10, 11
Stable or unstable: what the scan can and can't tellEmerging evidence
Stable means the patch is still attached with intact cartilage; unstable means the cartilage has cracked, fluid has got behind the piece, or it has come loose. In adults, the MRI signs of instability are reliable: in 40 patients with an average age of 26, MRI picked out 35 of 36 unstable lesions.
In children the same signs over-call instability. In 36 lesions in children, the signs together caught every unstable lesion but labelled most stable ones as unstable too: only 11% of stable lesions were correctly called stable, against 100% in adults. Keyhole surgery is the final judge when it matters.
Sources 12, 13, 11
What scans can mistake for OCDEmerging evidence
In younger children, the end of the thigh bone hardens unevenly as it grows, especially at the back, and this can look like early OCD. In 38 children, 23 had bone defects suggestive of early OCD; the signs of a normal variant were extra small centres of bone, spiky edges and no swelling in the bone, and 22 of the 23 improved. Comparing with the other knee helps.
In 7 pain-free brothers and sisters of children with OCD, these variants were common and occasionally progressed to OCD, once needing surgery.
Sources 14, 15, 11
How it usually goesEmerging evidence
About half to three-quarters of stable lesions in children heal without surgery, depending on how studies define healing. In 47 stable lesions in children treated with a cast, then a brace and no running, jumping or sport, two-thirds were healing at 6 months. In a multicentre study of 185 knees, 77% avoided surgery; with strict criteria (complete healing on MRI and a full return to sport), 38% of 64 healed. Across 13 studies, success without surgery ranged from about 40% to 88%.
Older children do less well without surgery: 12 to 19 year olds were 7.4 times as likely as 6 to 11 year olds to need an operation. Larger lesions, and swelling, locking, catching or giving way at the start, made healing less likely. Across Europe, results were better in younger patients, and in a small older series, 3 of 5 knees with open growth plates did well without surgery against 1 of 9 with closed ones.
Sources 16, 17, 18, 19, 20, 21, 22