What it is
The growth plate at the top of the thigh bone is weaker than the bone around it. In SUFE, the ball (the epiphysis) slips backwards and downwards off the neck of the bone through the growth plate, a bit like a scoop of ice cream slipping off a cone. It usually happens in the growth spurt around puberty.
It usually develops gradually over weeks or months, but it can happen suddenly, sometimes after a minor fall. The UK name is slipped upper femoral epiphysis (SUFE); in North America it is slipped capital femoral epiphysis (SCFE).
Sources 1, 2, 3, 4
Who gets itStrong evidence
In a UK national study, 486 children (513 hips) were newly treated in Great Britain over 18 months: about 3 in every 100,000 children aged 6 to 18 each year. The median age was 12.7, with slightly more boys, and a US orthopaedic society gives 12 to 16 for boys and 10 to 14 for girls.
Being very overweight (obesity) is the main risk factor: it was recorded in 26% of the UK children. An underactive thyroid (1.9%) and other hormone conditions (1.5%), Down's syndrome (0.9%) and previous radiotherapy are rarer causes. But it isn't only a weight problem: in a US series of 193 children, a third linked the start of their symptoms to sport, most often basketball, and their weight was slightly lower than the others'.
Sources 5, 1, 6
How it shows: knee pain can be the only signEmerging evidence
Pain in the groin, hip, thigh or knee, often for weeks, worse with activity; a limp; a foot that turns outwards; and less movement at the hip, especially turning it inwards. Children may feel as if they've pulled a muscle.
Some children only have knee pain. In 106 US children, 15% first had pain in the knee or lower thigh, and they were more often misdiagnosed, had more unhelpful X-rays and had worse slips. In other US studies, knee pain went with longer delays, and in a matched comparison of 290 children, those with knee pain waited on average about 92 days longer for a hip X-ray and 82 days longer for surgery, and later needed more hip operations. A GP referral guide says to always examine the hip in any child or teenager with knee pain, and a US review says a groin strain is rare at this age.
Sources 1, 7, 8, 9, 10, 11, 12, 13, 14, 15
Delays are common, and they make it worseStrong evidence
In the UK study, 344 of 486 children waited more than a week from their first symptoms to treatment. Of 311 descriptions of the delay, 98 were families not seeking help yet, 96 were repeat visits with a first diagnosis such as a groin sprain or growing pains, 28 were X-rays first thought to be normal, and 26 were slips referred without urgency. In stable slips, the longer the wait, the worse the slip: a median of 1 month to diagnosis for mild slips, 2 for moderate and 3 for severe.
It's the same elsewhere: in Melbourne the diagnosis was missed at the first visit in 60% of 103 stable slips, and in 481 US children symptoms had lasted 17 weeks on average before diagnosis, with no improvement over a decade.
Sources 5, 16, 17
Stable and unstable slips, and what the X-rays show
Doctors call a slip stable if the child can put weight on the leg, with or without crutches, and unstable if they can't, even with crutches. Most are stable; 21% were unstable in the UK study. An unstable slip usually comes on suddenly with severe pain and a leg turned outwards, and it is much more likely to damage the blood supply to the ball.
X-rays of both hips confirm it, and a side view with the legs in a frog position picks up mild slips that a front view can miss. If the X-rays look normal but the symptoms fit, an MRI (magnetic resonance imaging) scan can catch a very early slip.
Sources 1, 5, 2, 15, 18
What happens after treatmentStrong evidence
The main worry is avascular necrosis: loss of the blood supply to the ball, which can make it collapse. Within 2 years in the UK study, it affected 7.1% of hips overall, 23% of unstable hips, 11.8% of stable hips that had open surgery to reposition the ball, and 1.8% of stable hips fixed where they lay. It may not show on X-ray for 12 to 18 months.
Other problems were rarer: rapid loss of the joint cartilage in 0.8%, a wound infection in 0.9%, and a screw entering the joint or working loose in about 1% each. By 2 years, 16% had had further surgery, and 2.5% had had or were waiting for a hip replacement.
Sources 5, 1
The other hipStrong evidence
In the UK study, 33 of 286 other hips that weren't fixed (11.5%) were operated on for a slip within 2 years, and being younger, under about 12.5, was the only predictor. A second slip happened in 10.8% of a US series, and in 43 of 201 hips under regular follow-up in Sweden. If the other side slips, it is usually within 18 months.
Sources 5, 17, 19, 1