What it is, and the stages
The lunate is one of the eight small wrist bones, in the middle of the wrist between the forearm and the hand. In Kienböck's disease its blood supply is interrupted, and the bone loses its strength and can collapse, causing a painful, stiff wrist; over time, arthritis develops in the bones around it. It is named after Robert Kienböck, a radiologist who described it in 1910.
Treatment is planned by stage (the Lichtman stages), and newer systems add a contrast MRI scan (how much blood flow is left) and keyhole surgery (whether the cartilage is intact), which surgeons use to choose an operation.
- Stage I: symptoms like a sprain; X-rays may look normal, and an MRI scan shows the change in blood flow.
- Stage II: the lunate looks denser on X-ray, with pain and swelling, especially taking weight through the wrist.
- Stage III: the lunate collapses or breaks up (IIIA), then the bones around it shift (IIIB).
- Stage IV: arthritis in the wrist.
Sources 1, 2, 3
Who gets itEmerging evidence
It is rare. In Finland, from 1996 to 2022, about 1 person in 100,000 a year was diagnosed (9.6 per million), most often at 50 to 59, and men had 24% more cases than women. Among 51,071 people whose wrists were imaged at one US hospital over 11 years, 0.27% had Kienböck's, men and women about equally; 37% of them had no symptoms from it. In 350 people who had surgery for it, 2.9% had it in both wrists.
Teenagers and adults over about 70 have a better outlook; in older adults it affects women more often, and it goes with thinning bones (osteoporosis) and inflammatory and autoimmune conditions.
Sources 4, 5, 6, 2, 7
Why it happensMixed evidence
The cause is unknown. Reviews describe an 'at-risk' lunate (a single blood vessel to it in some people, the shape of the bone, and the relative lengths of the forearm bones) meeting a trigger. A forearm bone that ends shorter at the wrist is often blamed, but one review reports that it is common in people without the disease, so most people who have it never develop Kienböck's.
In Finland, a previous hand or wrist injury came with about 3 times the odds, though Kienböck's after a single injury is rare and reported mostly in single cases. Alcohol misuse, rheumatic diseases and clotting disorders were also linked. A systematic review of 152 articles found no good evidence that vibrating tools cause it, and it isn't on the UK list of prescribed industrial diseases. US surgeons describe extra pressure on the lunate in push-ups in people with uneven forearm bones.
Sources 2, 8, 5, 9, 10, 11, 1
How it's diagnosed, and what scans do and don't meanEmerging evidence
The symptoms are wrist pain, swelling, stiffness, a weaker grip and tenderness over the middle of the back of the wrist. It usually progresses slowly, and many people think they've sprained the wrist at first. An NHS hand clinic describes the pain as usually dull and constant, worse with use and better, but not gone, with rest.
X-rays come first, but in stage I they can be normal: an MRI scan shows the change, and a CT (computed tomography) scan shows collapse. Even with special scans, the early diagnosis isn't always clear. Kienböck's changes can also turn up by chance: 37% of the cases found at one hospital caused no symptoms, and the symptoms didn't reflect how severe the changes were. The diagnosis and stage come from your symptoms, the examination and the scans together, read by a hand specialist.
Sources 1, 3, 2, 6
How it usually goesEmerging evidence
Left alone, the lunate tends to move through the stages over years. A review describes pain and swelling that come and go, then persistent pain, then settling as arthritis develops, over 5 years or more, and says symptoms generally ease with time even without treatment.
In a long-term series of 49 wrists, 83% of those treated in plaster and 77% of those left untreated were pain-free or painful only with heavy work, although every lunate was deformed and 67% had arthritis. An NHS hand clinic says some lunates partly regain their blood supply and stay stable, while others collapse. In Finland, 44% of people had an operation, and 19% of those had more than one. US surgeons say not to expect a fully normal wrist, but that treatment gives the best chance of long-term pain relief and keeping function.
Sources 2, 12, 3, 4, 1