Pain guide · Knee pain

Exercises after knee cartilage surgery: microfracture, cell transplants (ACI) and grafts

This guide is about operations on the smooth cartilage that covers the ends of the bones: microfracture, cell transplants (autologous chondrocyte implantation, ACI) and grafts of bone and cartilage. If you had a torn meniscus trimmed or repaired, our meniscus surgery guide is the one you need. Recovery is long: the new surface is protected for about the first 6 weeks, usually with crutches and sometimes a brace, and the full rehab takes 6 to 12 months.

Your surgical team's plan comes first: the weight you can take and how far you can bend depend on the operation and where the damage was. This guide sets out the usual stages from NHS and specialist protocols, with a 3D demo of each exercise, what trials found about putting weight through the leg, the return to sport, what a scan after surgery does and doesn't mean, and the signs of a blood clot and other warning signs.

When to get help first

Exercise is for pain that has been checked or is clearly mild and settling.

Get urgent medical help if

  • Leg pain or swelling with breathlessness or chest pain: call 999 or go to A&E, and do not drive yourself. It can be a blood clot that has reached the lungs.
  • Throbbing pain and swelling in one calf or thigh, with red or darkened skin or swollen veins: ask for an urgent GP appointment or get help from NHS 111, as it could be a blood clot. Call 999 or go to A&E if you are also short of breath or have chest pain.
  • After the operation: a high temperature, or feeling hot, cold or shivery; severe or increasing knee pain; smelly white, yellow or brown liquid leaking from a cut; severe or worsening swelling or redness in or around the knee; or numbness or tingling in or around it. Contact NHS 111, or the hospital where you had the operation.
  • A hot, red or swollen knee with sudden severe pain, a very high temperature, or feeling hot, cold or shivery. This can be a joint infection.
  • The knee is locked and you cannot fully straighten it. After cartilage surgery, contact your surgical team the same day.
  • In a brace or bandage: toes that turn numb, cold, pale or blue, or a brace or bandage that feels too tight. Get advice the same day from your hospital or NHS 111.
  • You fall or twist the knee and then can't put weight on it, or it becomes very painful, badly swollen or changes shape: get advice from NHS 111 or your surgical team now.

See a doctor or physiotherapist if

  • In a brace: sore skin, pressure marks, or a brace that no longer fits as the swelling goes down. Tell your physiotherapist or orthotics team.
  • Swelling that keeps building as you do more, or doesn't settle overnight: do a little less, and tell your physiotherapist if it doesn't settle.
  • The knee isn't getting fully straight in the first weeks, or its bend isn't improving within your limits: tell your physiotherapist or surgical team.
  • New catching, clicking with pain, or swelling months after the operation: see your surgical team. Occasionally a graft or the repair tissue loosens.
  • A flight or long journey in the first weeks: ask your team about your risk of a blood clot first. One NHS trust advises no flying for 8 weeks after microfracture.
  • You're not sure what your limits are, or you're not reaching the stage your team expected: ask them rather than guess.

Understand it

Which cartilage this is about

Articular cartilage is the smooth, shiny layer on the ends of the bones, and this guide is about surgery on it. The meniscus is the C-shaped cushion between the bones: the NHS page on knee cartilage damage is about meniscus tears, and our meniscus surgery guide covers those operations. Your operation note or your surgeon can tell you which you had.

Sources 1, 2

Why a damaged patch is repaired

Damage to the joint surface can follow an injury, especially a sports injury in young people, or come from osteochondritis dissecans or an unstable kneecap. It can cause pain, swelling, a knee that gives way, catching or locking, and it may lead to osteoarthritis over time. Cartilage doesn't heal itself well, which is why surgery tries to fill the defect.

Sources 3, 2

The three kinds of operation

These operations are often combined with others, such as straightening the leg or rebuilding a ligament, which bring their own limits.

  • Microfracture or drilling: small holes are made in the bone at the base of the defect. A clot forms, and new cells fill the gap with repair tissue called fibrocartilage, which one NHS trust describes as not exactly like the original cartilage but a better surface than bare bone. It's keyhole surgery, usually as a day case, and the American Academy of Orthopaedic Surgeons (AAOS) says it suits small defects in less active people.
  • Autologous chondrocyte implantation (ACI): healthy cartilage cells are taken at a first keyhole operation, grown in a laboratory for about a month, and put into the defect at a second operation, often on a membrane (matrix-induced ACI, or MACI).
  • Bone and cartilage grafts: in mosaicplasty or an osteochondral autograft transfer (OAT), small plugs of cartilage with the bone beneath are moved from a less-loaded part of the knee into the defect. Plugs from a donor (an allograft) are used for larger defects.

Sources 4, 2, 5, 3

Who has it

The National Institute for Health and Care Excellence (NICE) says supportive care comes first: exercise, weight loss, physiotherapy, painkillers, injections and braces that take the load off. Surgery is considered only if symptoms persist. NICE recommends ACI only for people who haven't had cartilage repair surgery before, with minimal arthritis and a defect larger than 2 cm², in a specialist centre.

The AAOS says most people who have these operations are young adults with a single damaged patch, and that an earlier microfracture can make a later restoration work less well. In a UK trial, an earlier operation that stimulates the bone marrow, such as microfracture, worsened the results of ACI at 5 years, though not in the ACI group at 10 years.

Sources 5, 6, 2, 7, 8

What recovery usually looks like

NHS and specialist protocols agree on the shape of recovery, with different timings. Your own team's plan comes first.

  • Weeks 0 to 6: the new surface is protected, usually with crutches and limited weight, sometimes a brace, with gentle exercises 3 to 4 times a day.
  • Weeks 6 to 12: off the crutches as your team allows, walking normally, the bike, step-ups and early strength work.
  • Months 3 to 6: strength and single-leg control, with running from about 12 to 20 weeks or later, depending on the operation.
  • Months 6 to 12: agility, then sport. Rehab takes 6 to 12 months, and one NHS trust says full recovery after microfracture can take 12 to 18 months.

Sources 9, 10, 4, 11, 12

Long-term resultsEmerging evidence

In a Norwegian trial of 80 people, ACI and microfracture did the same at 14 to 15 years, and about half the knees still working had early arthritis on X-ray (57% and 48%). For defects of 3 cm² or more, MACI did better than microfracture on pain and function at 2 and 5 years, in a trial of 144 people. For medium and large defects, results after microfracture declined over 10 years or more, with arthritis getting worse in 40% to 48%.

In a UK trial of 390 people whose first cartilage operation hadn't worked, ACI and other surgery did the same at 5 years. At 10 years, ACI was ahead by 7.3 points on a 100-point knee score, but once later operations were allowed for, the difference shrank to 3.8 points, which could be no real difference at all. Failure rates were similar (29% and 25%). Only the abstract of the 10-year report was available.

Sources 13, 14, 15, 16, 7, 8

What a scan after surgery does and doesn't meanEmerging evidence

In a review of 32 studies (1,019 people), most magnetic resonance imaging (MRI) measures of a cartilage repair matched how people did poorly or not at all. In one trial, MACI felt better than microfracture, though the defects looked similarly filled on MRI. So incomplete filling on a scan doesn't on its own mean the repair has failed, and a well-filled defect doesn't guarantee a pain-free knee.

The exception is a mechanical problem: a graft can lift off (delamination, in about 5 in 100 after MACI, usually in the first 6 months), which can cause new catching or locking and needs your team.

Sources 17, 15, 18

What helps, and how strong the evidence is

Protected weight-bearing: plans vary, and earlier full weight was safe in trialsEmerging evidence

NHS and US plans range from full weight with crutches to partial weight (about half your body weight) or none for the first 6 weeks. After MACI, one US hospital's guideline builds from 20% to 75% of body weight over 6 weeks, and NICE says no weight for 4 to 8 weeks is usual after mosaicplasty. Across US protocols, full weight was allowed at an average of about 6 weeks after microfracture of the thigh bone, sooner for the kneecap joint, and at 5 to 6 weeks after grafts. Most trials of ACI used partial weight straight away and full weight within 12 weeks.

In trials from one Australian group, reaching full weight 8 weeks after MACI did as well as 11 weeks at 2, 5 and 10 years, and 6 weeks did as well as 8 weeks, with no harm to the graft. These are small trials in specialist hands, so keep to the limits your team sets.

Sources 9, 11, 3, 19, 20, 21, 18, 22, 23, 24, 25

Small microfracture defects: limits may matter lessMixed evidence

In a study of 43 small defects, taking weight as comfortable without a continuous passive motion (CPM) machine did as well as 6 weeks without weight and with the machine. A review concludes that weight limits may not be needed for small defects on the main weight-bearing surfaces, but the evidence is low level, so your team's limits still apply.

Sources 26, 27

Going back to sportEmerging evidence

Across 2,549 athletes, 76% went back to sport: 93% after an osteochondral autograft (at about 5 months), 88% after a donor graft (about 10 months), 82% after ACI (about 12 months) and 58% after microfracture (about 9 months). An earlier review found 73% went back, at 7 to 18 months. In 7 trials (346 people), autografts gave a better return to sport and fewer failures than microfracture. These reviews pool mostly low-quality studies.

NHS and US protocols set criteria rather than dates: running from about 12 to 20 weeks, and competitive sport from about 20 weeks after microfracture in one NHS protocol, once strength and control allow and the knee isn't swelling.

Sources 28, 29, 30, 12, 11

Injections added to surgery: uncertainMixed evidence

In 11 studies (6 of them trials, 664 people), adding platelet-rich plasma (PRP) to microfracture improved pain and function scores at some time points but not others, and the authors call for better studies. It's an add-on with uncertain benefit.

Source 31

Blood clots: medicine for someStrong evidence

NICE says medicine to prevent clots is generally not needed after keyhole knee surgery when the anaesthetic is under 90 minutes and the risk is low, and to consider it for 14 days when the operation is longer or the risk is higher, and for other knee surgery when the risk of a clot outweighs the risk of bleeding. One NHS trust gives daily injections for about 14 days when they're needed, and advises no flying for 8 weeks after microfracture.

Sources 32, 4

How much pain is OK while you exercise?

Pain-free in the joint, and watch the swellingEmerging evidence

One NHS trust's leaflet says the exercises should be pain-free, and a US hospital's guideline says to avoid pain during exercise and daily activities, with no pain or swelling after activity before moving on. Another NHS leaflet says extra discomfort for up to an hour after the exercises is normal, and another says to avoid activities that are painful and make the knee swell.

So, borrowed from our knee osteochondritis dissecans (OCD) guide's rule: for walking, running and jumping, no pain in the knee joint during, straight after or the next morning; for strength exercises, no pain in the joint, though a working ache in the thigh or hip muscles that settles within the hour is fine. Catching, locking, giving way, new swelling, or a knee that doesn't straighten as far as before are never part of the rule: stop and contact your team.

Swelling is the other gauge, borrowed from our anterior cruciate ligament (ACL) guide: measure round the middle of both knees with a soft tape, and if the operated knee is more than about 1 cm bigger after a session, let it settle before carrying on. This is stricter than our knee pain hub's rule for long-standing knee pain, because the joint surface is healing.

Sources 9, 11, 10, 4

The exercise plan: 4 stages

Start at the first stage. Each move opens a full guide with a 3D demo.

Stage 1

Protect the new surface: crutches, the brace and gentle movement (about weeks 0 to 6, as your team allows)

As your team allows. Keep exactly to the weight your team sets for about the first 6 weeks: none, part of your weight, or full weight with crutches, depending on the operation and where the defect is. Wear any brace as you're told, often all the time, including at night. Get the knee fully straight, get the bend back within your limits, and keep the thigh working, with the exercises 3 to 4 times a day. Keep the leg raised with nothing under the knee, and use ice for 15 to 20 minutes. The exercises should be pain-free; some extra discomfort for up to an hour afterwards is normal.

Ankle circles demonstrated on the 3D figure3D demoAnkle circlesBeginner · No equipment

Pump the ankle up and down 10 times every waking hour · An NHS leaflet's dose; up-and-down pumps rather than the move page's circles

Harder: Ankle CARs (controlled articular rotations)

Quad set (static quads) demonstrated on the 3D figure3D demoQuad set (static quads)Beginner · No equipment

Hold 10 s, 10 times, 3 to 4 times a day · An NHS leaflet's dose

Harder: Straight-leg raise

Supine heel slide demonstrated on the 3D figure3D demoSupine heel slideBeginner · No equipment

10 slides, 3 to 4 times a day, only within your bending limit · An NHS leaflet's dose, a little more often than the move page's

Harder: Hip windshield wipers

Straight-leg raise demonstrated on the 3D figure3D demoStraight-leg raiseBeginner · No equipment

Hold 5 s, 10 times, when your team says · NHS leaflets' dose

Easier: Quad set (static quads) · Harder: Leg extension

Side-lying leg raise demonstrated on the 3D figure3D demoSide-lying leg raiseBeginner · No equipment

10 times, operated leg on top, when your physiotherapist says · An NHS leaflet's dose

Easier: Lateral band walk · Harder: Lateral band walk, band at the feet

Move on when: Your team lifts the weight limit (often at about 6 weeks, sooner after some operations and later after others), you can lift the straight leg without the knee bending, the swelling is settling, and the knee straightens fully.

Follow along: a timer, a cue and the next move, one step at a time.
Stage 2

Walking well and early strength (about weeks 6 to 12, as your team allows)

As your team allows. Come off the crutches as your team says, and walk normally, heel first and without a limp. Get the bend back. Start loading the leg standing up: in an NHS and a US protocol, the bike, step-ups, chair squats and a light leg press start in or just before this window. Keep exercises out of any range your team gives you to avoid. Doses are editorial.

Stationary cycling demonstrated on the 3D figure3D demoStationary cyclingBeginner · Cardio machine

10 to 20 minutes, easy, with the saddle high · Editorial dose

Easier: Recumbent exercise bike · Harder: Air bike intervals

Sit to stand from a chair demonstrated on the 3D figure3D demoSit to stand from a chairBeginner · A bench or box

2 to 3 sets of 10, from a higher chair at first · Editorial dose

Easier: Sit to stand, pushing on the thighs · Harder: Bodyweight squat

Leg press demonstrated on the 3D figure3D demoLeg pressBeginner · Strength machine

Light, 3 sets of 10 to 12, in the range your team allows · Editorial dose

Harder: Bodyweight squat

Low step-up demonstrated on the 3D figure3D demoLow step-upBeginner · A step

2 sets of 10 on each leg, from a 10 cm step, building towards 20 cm · Editorial dose; a US guideline builds the step height the same way

Harder: Step-up

Single-leg stand demonstrated on the 3D figure3D demoSingle-leg standBeginner · A wall

3 holds of up to 30 s, near a support · Editorial dose

Easier: Tandem stance and heel-to-toe walk · Harder: Single-leg reach matrix

Move on when: You walk normally, have full movement (or as much as your team allows), and can step up onto a 20 cm step, squat evenly to a right angle and stand on the operated leg for more than 30 seconds, with no swelling after sessions. These are a US hospital's criteria.

Follow along: a timer, a cue and the next move, one step at a time.
Stage 3

Strength and single-leg control (about months 3 to 6, as your team allows)

As your team allows. Heavier and single-leg strength work 2 to 3 times a week, keeping the knee in line over the middle of the foot, and low-impact cardio such as the cross-trainer. In one NHS protocol after microfracture of the kneecap groove, strength without range limits starts at 12 weeks, with light jogging, changes of direction and jumping drills from 12 to 16 weeks; a US guideline starts running from about 20 weeks after MACI. Doses are editorial unless named.

Dumbbell goblet squat demonstrated on the 3D figure3D demoDumbbell goblet squatIntermediate · A dumbbell

3 sets of 8 to 12, to a box at first, going deeper over the weeks · Editorial dose

Easier: Bodyweight squat · Harder: Barbell front squat

Split squat demonstrated on the 3D figure3D demoSplit squatIntermediate · No equipment

3 sets of 8 on each leg, holding a support · Editorial dose

Easier: Bodyweight squat · Harder: Reverse lunge

Patrick step-down demonstrated on the 3D figure3D demoPatrick step-downIntermediate · A step

3 sets of 8 to 10 on each leg, from a low step · Editorial dose

Easier: Bodyweight squat · Harder: Skater squat

Elliptical trainer demonstrated on the 3D figure3D demoElliptical trainerBeginner · Cardio machine

10 to 20 minutes at a moderate effort, building towards 30 · The move page's dose

Harder: Stair-stepper machine

Move on when: Thigh strength is at least 80% of the other side's (a physiotherapist can test it), there's no pain or swelling after activity, and you can step down from 20 cm and squat on one leg to 45 to 60° with control. These are a US hospital's criteria.

Follow along: a timer, a cue and the next move, one step at a time.
Stage 4

Running, landing and sport (often from about 4 to 6 months, as your team allows)

As your team allows. Running starts from about 12 to 16 weeks after microfracture of the kneecap groove in one NHS protocol, and from about 20 weeks after MACI in a US hospital's guideline. Agility, cutting and twisting come next, and competitive sport from about 20 weeks after that microfracture. Across studies, going back to sport took about 5 months after an osteochondral autograft and about 12 months after ACI. Doses are editorial unless named.

Treadmill jogging demonstrated on the 3D figure3D demoTreadmill joggingIntermediate · Cardio machine

Walk-jog intervals every other day, building to continuous running; stop if the knee swells · Editorial dose

Easier: Treadmill walking · Harder: Sprint intervals

Snapdown to athletic landing demonstrated on the 3D figure3D demoSnapdown to athletic landingBeginner · No equipment

2 to 3 sets of 5, freezing each landing · Editorial dose

Harder: Box drop landing

Single-leg hop and stick demonstrated on the 3D figure3D demoSingle-leg hop and stickIntermediate · No equipment

3 sets of 5 on each leg, forwards then sideways · Editorial dose

Easier: Standing broad jump with stuck landing · Harder: Alternate-leg bounding

Lateral bound (skater jump) demonstrated on the 3D figure3D demoLateral bound (skater jump)Beginner · No equipment

3 sets of 6 to 8 bounds (3 or 4 on each leg), resting a minute between sets · The move page's dose

Harder: Bench jump-over

Shuttle runs demonstrated on the 3D figure3D demoShuttle runsAdvanced · No equipment

Short sets with wide, easy turns at first, building speed over the weeks · Editorial dose

Easier: Treadmill jogging

Move on when: Your team clears you for sport: no swelling or pain in the joint after training, full movement, and strength and hops close to the other leg's (90% in a US hospital's guideline). Keep a strength day or two a week, and use a knee control warm-up before pivoting sport.

Follow along: a timer, a cue and the next move, one step at a time.

What to change for now

Typical timings, which your team may change

These come from NHS leaflets, NICE and a US hospital's guideline, and they differ. Your own team's timings come first.

  • Weight: limited for about the first 6 weeks, from none to full weight with crutches, depending on the operation and where the defect is.
  • Walking: no more than 15 minutes at a time in the first week, in one NHS leaflet.
  • Driving: not for at least 6 weeks while your weight is limited, in one NHS leaflet; then once you're walking without crutches and can do an emergency stop. After surgery on the left knee, with an automatic car, one trust allows it once the wounds have healed. Tell your insurer.
  • Work: a desk job within days to a couple of weeks if you can keep your leg up; jobs on your feet usually wait until your weight limits are lifted.
  • Flying: not for 8 weeks after microfracture, in one NHS leaflet.
  • Running: from about 12 to 20 weeks, depending on the operation. Competitive sport: from about 20 weeks after microfracture in one NHS protocol, and about a year on average after ACI in studies.

Sources 9, 10, 4, 3, 12, 11

Letting the knee straighten: the heel prop (written steps)

From the Gateshead and Worcestershire NHS leaflets.

  • 1. Sit with the heel of the operated leg resting on a stool or a rolled towel, with nothing under the knee.
  • 2. Let the leg relax and straighten. If your team says, gently tighten the thigh to straighten it a little more.
  • 3. Hold for 5 to 10 seconds, 10 times (Gateshead), or for 30 seconds, 3 times (Worcestershire).
  • 4. When you rest, keep the knee straight, with the whole leg supported. Never put a pillow under the knee.

Sources 10, 9

Kneecap glides (written steps)

From the Worcestershire NHS leaflet, with our suggestion marked.

  • 1. Only if your team includes them; after an operation on the kneecap itself, ask first (our suggestion).
  • 2. Sit with the leg straight and supported, and let all the muscles relax.
  • 3. With your hand on the top edge of the kneecap, gently push it towards your foot. Hold 5 seconds, 10 times.
  • 4. With the edge of your thumb, gently push it towards your other leg. Hold 5 seconds, 10 times.
  • 5. Then gently push it outwards. Hold 5 seconds, 10 times.

Source 9

Bending the knee without its own muscles (written steps)

From the Worcestershire NHS leaflet. Some teams use a continuous passive motion (CPM) machine to bend the knee for you in the first weeks, as most ACI trials did; this is the home version.

  • 1. Choose one way, not both. Sitting on the floor or a bed with the leg out, loop a towel or belt round the heel of the operated leg. Or sit on a chair with your good leg hooked in front of the operated one.
  • 2. Gently pull with the towel, or push back with the good leg, to bend the operated knee until you feel a stretch, never past your team's limit or your brace's setting.
  • 3. Slide it back out straight.
  • 4. Repeat 500 times, 3 times a day, as one NHS leaflet suggests. It does the job of a machine that bends the knee for you.

Sources 9, 21

Crutches and stairs (written steps)

From the Liverpool NHS leaflet. Take only the weight your team allows through the operated leg.

  • 1. On the flat: move the crutches and the operated leg first, then let the good leg follow, putting only the weight your team allows through the operated leg.
  • 2. Upstairs: hold the banister with one hand and the crutches (or a stick) in the other. Step up with the good leg first, then bring up the operated leg and the crutches.
  • 3. Downstairs: the crutches and the operated leg go down first, then the good leg.
  • 4. Keep the crutches on the same step as the operated leg.

Source 4

Routines that fit, and what to leave out

From about 6 weeks: the cardio intervals workout (on the bike), the low-impact leg workout and the balance exercises routine; skip the leg workout's wall sit if your defect is on the kneecap or its groove, until your team allows. From about 3 months: the knee strengthening workout, leaving out its heel-elevated deep squat and reverse Nordic until your team allows deep bending (our meniscus surgery guide makes the same exception), and its wall sit with a kneecap or groove defect. Save the knee control warm-up for the return to sport.

Positions to swap, and why

Habit or positionWhy it mattersInstead
Putting more weight through the leg than your team allows in the first 6 weeksThe new surface needs protecting while it forms. The trials of earlier weight-bearing were planned protocols in specialist centres.Crutches, with only the weight you're allowed.
Bending past your limit, or outside the brace's settingLimits protect the repaired area, especially on the kneecap or its groove.Heel slides within your limit, and bending the knee with a towel.Try: Supine heel slide
A pillow under the kneeThe knee can stiffen bent; NHS leaflets say rest with it straight.The heel prop in the written steps.
Deep squats before your team allows deep bendingDeep bending loads the joint surface heavily (our reasoning).The bike, and a leg press in the range your team allows.Try: Leg press
Wall sits with a kneecap or groove defect, before your team allowsHolding a bent knee under load presses the kneecap into its groove (our reasoning); one NHS protocol keeps thigh exercises out of the defect's range.The bike, in the range your team allows.Try: Stationary cycling
Knee extensions against a weight with a kneecap or groove defect, before your team allowsThey load the kneecap joint through a range your team may want to avoid.Tightening the thigh with the leg straight.Try: Quad set (static quads)
The reverse Nordic, before your team allows deep bendingIt bends the knee deeply under load (our reasoning).Split squats in a short range.Try: Split squat
Long walks in the first weekOne NHS leaflet advises no more than 15 minutes at a time in the first week.Short, frequent walks on crutches.
Running and jumping before your team allowsProtocols wait until about 12 to 20 weeks, and a graft can lift off in the first months.The cross-trainer and the bike.Try: Elliptical trainer
Pushing through pain or swelling in the jointPain in the joint, swelling or catching means the healing surface is being overloaded.Drop back a step, not to nothing.

Routines to follow

More moves for this area

Questions people ask

Is knee cartilage surgery the same as meniscus surgery?

No. This guide is about the smooth cartilage on the ends of the bones. The NHS's knee cartilage damage page is about meniscus tears, the cushions between the bones, and our meniscus surgery guide covers those. Your operation note or surgeon can tell you which you had.

How long does recovery from microfracture take?

The new surface is protected for about the first 6 weeks, usually with crutches. Rehab takes 6 to 12 months, and one NHS trust says most people notice a big improvement by 6 months, but full recovery can take 12 to 18 months.

Why can't I put weight on my leg?

The clot or graft that forms the new surface needs protecting while it settles in, so most teams limit weight for about 6 weeks. How much depends on the operation and where the defect is: defects on the kneecap often allow more weight than those on the main weight-bearing surfaces. Follow your team's limits exactly.

How long is recovery after ACI or MACI?

ACI means two operations, and recovery is long. Weight is built up over about 6 to 12 weeks, running may start from about 20 weeks, and going back to sport took about 12 months on average in studies. In trials, people were still doing well 10 years later.

Do I need a CPM machine?

Some teams use a continuous passive motion (CPM) machine to bend the knee gently in the first weeks. Others ask you to bend it yourself with a towel or your other leg, many times a day. For small defects, going without a machine did no worse in one study.

When can I drive after knee cartilage surgery?

Usually not while your weight is limited: one NHS trust says at least 6 weeks. You need to walk without crutches and be able to do an emergency stop, and you should tell your insurer.

When can I run and play sport again?

Running often starts from about 12 to 20 weeks, and competitive sport from about 5 months after microfracture in one NHS protocol. Across studies, 76% went back to sport: fastest after a graft from your own knee (about 5 months) and slowest after ACI (about a year). Your team decides, often using strength and hop tests.

Will my new cartilage be as good as the original?

Not exactly: microfracture makes a tougher, less smooth repair tissue called fibrocartilage. Many people still do well. Results after microfracture of larger defects tend to decline over the years, while grafts and cell implants held up better in some trials.

My MRI says the defect isn't fully filled. Has the operation failed?

Not necessarily. Most MRI measures of a cartilage repair match how people feel poorly, and in one trial, two operations with similar filling on MRI felt different. Your surgeon will weigh the scan alongside your symptoms.

Will I get arthritis in that knee?

Some people do, years later: in a 15-year trial, about half the knees still working had early signs of arthritis on X-ray after either ACI or microfracture. Keeping the thigh strong and staying active within your team's advice gives the knee its best chance.

When can I go back to work?

A desk job may be possible within days to a couple of weeks if you can keep your leg up. Jobs on your feet usually wait until your weight limits are lifted and walking is comfortable. Your team will advise.

Related exercise guides

Other pain guides

Sources

  1. NHS · Meniscus tear (knee cartilage damage)
  2. AAOS OrthoInfo · Articular cartilage restoration
  3. NICE HTG463 · Mosaicplasty for symptomatic articular cartilage defects of the knee (2018)
  4. Liverpool University Hospitals NHS Foundation Trust · Microfracture for articular cartilage defects (leaflet, 2021)
  5. NICE TA477 · Autologous chondrocyte implantation for treating symptomatic articular cartilage defects of the knee (2017)
  6. NICE TA508 · Autologous chondrocyte implantation using chondrosphere for symptomatic articular cartilage defects of the knee (2018)
  7. Snow 2023 · Chondrocyte implantation against other cartilage surgery after a failed first operation: 5 years (ACTIVE randomised trial, Am J Sports Med)
  8. Snow 2026 · Chondrocyte implantation against other cartilage surgery: 10 years (ACTIVE randomised trial, Osteoarthritis Cartilage)
  9. Worcestershire Acute Hospitals NHS Trust · Advice and exercises following microfracture of the knee (leaflet, 2024)
  10. Gateshead Health NHS Foundation Trust · Post-operative knee microfracture (2025)
  11. Hospital for Special Surgery Rehabilitation · Knee articular cartilage MACI tibiofemoral post-operative guideline
  12. Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust · Rehabilitation protocol after trochlea microfracture (Wrightington Sports Knee Clinic)
  13. Knutsen 2016 · Autologous chondrocyte implantation against microfracture at 14 to 15 years (randomised trial, J Bone Joint Surg Am)
  14. Saris 2014 · Matrix-applied cultured chondrocytes against microfracture: 2 years (randomised trial, Am J Sports Med)
  15. Brittberg 2018 · Matrix-applied cultured chondrocytes against microfracture: 5 years (randomised trial, Am J Sports Med)
  16. Gopinatth 2024 · Long-term results of microfracture for medium to large knee defects (systematic review, J Exp Orthop)
  17. de Windt 2013 · Does an MRI scan predict outcome after knee cartilage repair? (systematic review, Am J Sports Med)
  18. Ebert 2010 · Traditional against accelerated rehabilitation after chondrocyte implantation: 2 years (randomised trial, Cartilage)
  19. Crowley 2021 · How rehabilitation varies after microfracture of the knee (review of protocols, Cartilage)
  20. Crowley 2022 · How rehabilitation varies after osteochondral grafts in the knee (review of protocols, Cartilage)
  21. Dhillon 2022 · The commonest rehabilitation plan after matrix-assisted chondrocyte implantation (systematic review, Arthrosc Sports Med Rehabil)
  22. Ebert 2012 · Accelerated against traditional weight-bearing after matrix-induced chondrocyte implantation: 5 years (randomised trial, Am J Sports Med)
  23. Ebert 2020 · Two approaches to full weight-bearing after matrix-induced chondrocyte implantation: 10 years (randomised trial, Am J Sports Med)
  24. Edwards 2013 · Accelerated weight-bearing after matrix-induced chondrocyte implantation: early results (randomised trial, Am J Sports Med)
  25. Ebert 2025 · A 6-week return to full weight-bearing after matrix-induced chondrocyte implantation: 10 years (randomised trial, Orthop J Sports Med)
  26. Marder 2005 · Two rehabilitation plans after microfracture of the knee (comparative study, Arthroscopy)
  27. Jain 2021 · Are weight-bearing limits needed after microfracture of the knee? (review, Sports Health)
  28. Krych 2017 · Return to sport after surgery for knee cartilage lesions (meta-analysis, Knee Surg Sports Traumatol Arthrosc)
  29. Mithoefer 2009 · Return to sport after knee cartilage repair (systematic review, Am J Sports Med)
  30. Han 2023 · Osteochondral autograft against microfracture in the knee (meta-analysis of randomised trials, Arch Orthop Trauma Surg)
  31. Mahamat Abdramane 2026 · Platelet-rich plasma with microfracture against microfracture alone (meta-analysis, Int J Surg)
  32. NICE NG89 · Venous thromboembolism in over 16s: reducing the risk of hospital-acquired DVT or pulmonary embolism (2018, updated 2019)
  33. NHS · DVT (deep vein thrombosis)

Exercise education, not a diagnosis or treatment plan. It is written from the guidelines and studies listed above; review by a clinician is pending. If your pain follows an injury, is severe, is getting worse, or comes with any warning sign listed on this page, get it assessed. Health disclaimer.