Narrowed leg arteries: intermittent claudicationStrong evidence
Peripheral arterial disease (PAD) is a build-up of fatty deposits that narrows the arteries supplying the leg muscles. Some people with it get "a painful ache in their legs when they walk, which usually disappears after a few minutes' rest", the NHS says, called intermittent claudication, in one or both legs. It's usually felt in the calf, but an NHS trust's leaflet says it can be in the thigh or buttock, depending on which arteries are narrowed.
Smoking is the biggest risk factor, with diabetes, high blood pressure, high cholesterol and age. The NHS says see a GP if you get recurring leg pain when exercising, because "Many people mistakenly think this is just part of growing older". Other signs include hair loss on the legs and feet, numbness or weakness, brittle, slow-growing toenails, wounds that don't heal, pale or blue skin and shiny skin.
Sources 1, 2
A strain, cramp or a clotEmerging evidence
A calf strain starts with a sudden, sharp pain in the back of the leg, then pain, swelling or bruising and difficulty or pain standing on your toes, an NHS trust's leaflet says. In 141 people scanned for suspected tennis leg, two-thirds had torn the inner head of the main calf muscle (the gastrocnemius), a few had torn the plantaris, and about 1 in 10 had a deep vein clot instead. Older age and a previous calf strain are the strongest risk factors for a calf strain in sport, in a review of mostly weak studies.
Cramp is a sudden, painful tightening that lasts from a few seconds to 10 minutes, mostly at night or at rest, and the muscle can feel sore for up to 24 hours. A deep vein thrombosis (DVT) causes throbbing pain and swelling in one leg, usually the calf or thigh, with red, blue or darkened skin or swollen veins.
Sources 3, 4, 5, 6, 7
The back, compartment syndrome, the Achilles and the restEmerging evidence
NHS inform says pins and needles or a sharp, hot or burning pain in the back of the calf can come from the back, even without back pain, and an NHS spinal service says spinal stenosis can cause aching or cramping in the calves, with heaviness in the legs on walking. Chronic compartment syndrome causes pain that comes on gradually with exercise and goes away with rest, the NHS says. Achilles tendon pain is felt along the cord above the heel, with stiffness in the morning and pain that worsens with activity.
Muscle pain is a common side effect of statins, and varicose veins can make your legs ache and feel heavy.
Sources 8, 9, 10, 11, 12, 13
How claudication is diagnosedStrong evidence
A GP looks at your legs and feet for shiny skin, brittle nails, hair loss, a weak or absent pulse and wounds, and compares the blood pressure at your ankle and your arm (the ankle brachial pressure index, ABPI). About 1 is healthy, and below 1 suggests narrowed arteries. More tests may be needed if the result is normal but the symptoms fit, if you're under 60 and have never smoked, or before a procedure.
The National Institute for Health and Care Excellence (NICE) says check the pulses in the groin, behind the knee and in the feet, and don't rule out peripheral arterial disease in someone with diabetes because of a normal or high ABPI alone. A duplex ultrasound scan comes first only when a procedure to open or bypass the artery is being considered.
Sources 14, 15
Tests for a clot or a tearStrong evidence
If a doctor thinks you have a DVT, the NHS says you should be referred to hospital within 24 hours for an ultrasound scan, and NICE asks for the result within 4 hours if possible when a clot is likely. Ultrasound can show a calf tear and rule out a clot: in the tennis leg study, it found a clot in about 1 in 10.
Sources 7, 16, 4
How it usually goesEmerging evidence
With claudication, 75% of people stay the same or improve, an NHS Scotland pathway says, and only 1 to 2 in 100 a year develop narrowing severe enough to threaten the leg, the Circulation Foundation says; walking distance usually improves over 3 to 6 months of regular walking, an NHS trust's leaflet says. The bigger risk is to the heart and brain: each year about 1 in 20 people with PAD has a heart attack or stroke or dies, which is why the medicines and stopping smoking matter.
Most sprains and strains feel better after 2 weeks, though strenuous exercise is best avoided for up to 8 weeks, and a cramp passes within 10 minutes. An NHS physiotherapy leaflet says most new leg pain improves within 6 to 8 weeks. No one can promise a date.
Sources 17, 18, 2, 19, 3, 6, 20