Exercise and feelings of energyMixed evidence
In a meta-analysis of exercise trials, regular exercise raised feelings of energy and lowered fatigue by a modest amount, but trials that compared exercise alone with a placebo-type activity found no effect, so expectation and attention may explain part of it. In 36 sedentary young adults with persistent tiredness and no diagnosis, 6 weeks of low or moderate intensity cycling 3 times a week raised energy similarly, and fatigue fell more with the lower intensity.
Sources 3, 4
Yoga in people without a fatigue-causing illnessEmerging evidence
In trials of older adults, yoga improved vitality a little compared with inactive groups. In 75 sedentary adults with arthritis, 8 weeks of yoga improved vitality compared with a waiting list. In students, morning yoga improved energy compared with a waiting list, but only 82 of 156 finished.
Sources 18, 19, 20
Cancer-related fatigueEmerging evidence
In women with breast cancer, yoga reduced fatigue compared with no therapy (11 studies, 883 women; moderate-quality evidence) and was no better than other exercise. Across cancers, a 2025 Cochrane review (21 trials, 2,041 people) found that yoga after treatment probably reduces fatigue in the short term, at moderate certainty, while its effect during treatment is very uncertain. A 2023 review of hatha and Iyengar yoga alone found no effect on fatigue, at low to very low certainty, so the style and the comparison matter.
The 2024 guideline from the American Society of Clinical Oncology (ASCO) and the Society for Integrative Oncology recommends exercise, cognitive behavioural therapy (CBT) and mindfulness for fatigue, and says yoga "may also be recommended" after treatment. Across 113 studies, exercise and psychological treatments both reduced cancer-related fatigue, and medicines didn't clearly.
Sources 6, 5, 21, 22, 23
The fatigue trial with supported posesEmerging evidence
In 31 breast cancer survivors with persistent fatigue, 12 weeks of twice-weekly 90-minute Iyengar classes centred on supported backbends and supported inversions, held for 5 to 10 minutes each, reduced fatigue and raised vigour compared with health education. One woman with a history of back problems had a back spasm in class.
Source 10
Multiple sclerosisEmerging evidence
Yoga reduced MS fatigue compared with usual care in two reviews (7 trials, 670 people; 10 trials, 693 people), and didn't differ from other exercise in either. In 69 people with MS, 6 months of weekly Iyengar classes, or of cycling classes, improved fatigue compared with a waiting list. A Cochrane review found exercise reduced MS fatigue without more relapses, and a 2025 review of 26 trials in autoimmune conditions also found yoga eased fatigue in MS.
NICE: "Advise people that aerobic, resistive and balance exercises, including yoga and pilates, may be helpful in treating MS-related fatigue".
Sources 7, 8, 24, 25, 26, 27
ME/CFS: clear guidanceStrong evidence
NICE says do not offer "any therapy based on physical activity or exercise as a cure for ME/CFS" or "generalised physical activity or exercise programmes", and not to advise exercise outside a programme overseen by an ME/CFS specialist team. The NHS says graded exercise therapy "is not recommended", and that there's no evidence resting completely helps.
Sources 15, 28
Isometric yoga in ME/CFS: one trialEmerging evidence
In 48 adults with ME/CFS that hadn't improved with usual care, about 12 weeks of isometric yoga lying down (25-minute sessions with an instructor at hospital visits, and daily at home) improved daily function and fatigue more than usual care alone, with no serious side effects. The trial wasn't blinded, and it's one trial: ask your ME/CFS team before trying it.
Source 16
Energising against restoring: no comparisonMixed evidence
We found no trial comparing energising and restorative yoga for energy. The restorative evidence is the fatigue trial's supported poses; the energising evidence is exercise in general. So choose by how you feel on the day.
Sources 11, 10, 3
Fast breathing: effects and cautionsEmerging evidence
In 20 healthy adults, heart rate and blood pressure rose during kapalabhati and bhastrika (bellows breath). In 38 experienced men, attention improved straight after fast yoga breathing. One healthy 29-year-old had a collapsed lung after kapalabhati, a single case report. NCCIH advises newcomers to avoid forceful breathing.
Sources 12, 29, 13, 14