No Pilates trial has published resultsStrong evidence
Our searches of PubMed, Europe PMC and ClinicalTrials.gov on 2 November 2026 found one trial: 18 people with injuries at T2 or below, more than 2 years after injury, randomised to 8 weeks of reformer Pilates with an instructor or a home exercise programme. It was completed in 2019, and no results have been posted or published.
Sources 3, 4
Pilates in wheelchair users with MSMixed evidence
In 15 wheelchair users with MS, 12 weeks of Pilates went with better sideways sitting balance, sitting posture and shoulder and back pain, and people enjoyed it. There was no comparison group, and MS isn't a spinal cord injury.
Source 2
A pilot in a spinal cord diseaseMixed evidence
In 8 people with HTLV-1 myelopathy, a spinal cord disease caused by a virus (human T-cell lymphotropic virus 1; 2 of them wheelchair users), 20 Pilates sessions over 10 weeks went with less pain and better balance, trunk control and quality of life, and "after 10 weeks without Pilates, there were significant changes in terms of increasing pain and regression of mobility". There was no comparison group.
Source 23
Trunk exercise and sitting balanceEmerging evidence
A 2025 review of 17 studies (432 people) found exercise improved static and dynamic sitting balance by large amounts (standardised mean differences of 1.21 and 1.01) and how far people could reach. We could read only its abstract: its search ended in June 2020, it mixed randomised and non-randomised studies, and one of its intervals doesn't contain its own estimate.
Newer trials are small: in 44 people in rehabilitation, 6 weeks of breathing muscle training improved sitting balance more than rehabilitation alone, and kayak ergometer and conventional trunk training improved trunk control about equally in 36 people. Seated trunk work, the Pilates-like part, is what has the support, and it improves sitting balance, not walking.
Sources 6, 24, 25
Exercise after spinal cord injury: the guidelinesStrong evidence
The 2018 guidelines rest on 211 studies, 189 of them in people injured more than a year earlier, with moderate confidence that exercise improves fitness, strength and heart health markers. For fitness and strength: "20 min of moderate to vigorous intensity aerobic exercise 2 times per week AND 3 sets of strength exercises for each major functioning muscle group, at a moderate to vigorous intensity, 2 times per week" (a strong recommendation). A 2026 Cochrane review of 17 trials (505 people) adds that training may increase fitness, with low certainty, and that its effects on quality of life, mood and harms are very unclear.
Sources 7, 26
Mood and quality of lifeEmerging evidence
In 19 trials (797 adults under 65), exercise improved overall wellbeing and quality of life by small to moderate amounts, with low certainty. In 3 of the studies, 4 serious side effects were probably caused by the exercise.
Source 27
Arm cranking does the cardioEmerging evidence
In 18 studies with 235 people, arm cranking for 30 to 40 minutes, 3 to 5 times a week, improved fitness with moderate certainty, and no evidence suggested it raises the risk of shoulder pain. Pilates doesn't replace this.
Source 28
Yoga and mind-body programmesMixed evidence
The one randomised trial of yoga alone (23 people, seated, 6 weeks) lowered depression with no change in pain, and "There were no adverse events reported." Across 5 studies of mind-body programmes, pain ratings fell by about 1.3 points on a 0 to 10 scale. No Pilates study has measured mood after spinal cord injury.
Sources 29, 30
Breathing muscle training is a different thingEmerging evidence
After a neck injury, training with a handheld device raised the amount you can breathe out (vital capacity) by about 0.4 litres and made the breathing muscles stronger, without changing breathlessness (11 studies, 212 people). A 2025 review agrees, noting the studies' "poor methodological quality". Pilates breathing is a relaxed breathing pattern, not this kind of training.
Sources 22, 31
Stretching paralysed limbsStrong evidence
Across 49 studies, high-quality evidence found regular stretching made no clinically important short-term difference to joint range in neurological conditions (about 2 degrees), and side effects included skin breakdown, bruising, blisters and pain. Spinal teams still use positioning and stretches for comfort and spasm, so follow their plan.
Source 20