Shoes and pads firstEmerging evidence
The NHS advises resting and raising the foot, ibuprofen or paracetamol, wide comfortable shoes with a low heel and soft sole, soft insoles or pads (ask a pharmacist for metatarsal pads), losing weight if you need to, and cutting down running and jumping. An NHS trust adds that the pad should sit behind the ball of the foot, not directly under it. A Welsh NHS podiatry service adds laced or strapped shoes with stiffer soles and a slight rocker, heels no higher than about 25 mm, and insoles with a metatarsal support built up over a week.
How well this works has hardly been tested. Across two small, low-quality studies, it succeeded in 32% (14% in one and 38% in the other), in line with the NHS trust's figure of about 1 in 3.
Sources 1, 4, 13, 11
Steroid injections: a short-term benefit in one trial, uncertain overallMixed evidence
In a UK trial of 131 people, a steroid and local anaesthetic injection, guided by ultrasound, improved overall foot health more than the anaesthetic alone at 3 months, by about 14 points on a 100-point scale.
Cochrane's 2024 review of 6 trials (373 people) is less sure: steroid with anaesthetic may make little or no difference to pain at 3 to 6 months compared with anaesthetic alone, and the certainty of that evidence is low. Side effects included thinning or lightening of the skin (each about 4 in 100) and thinning of the fat pad under the foot (about 3 in 100).
The reviews conflict on ultrasound guidance. A 2019 specialist review found it didn't seem to make injections more successful; Cochrane's 2024 review found guided injections probably reduce pain more than unguided ones (moderate certainty, 2 trials, 116 feet). The same 2019 review notes that about half of people given steroid injections may need surgery within 2 years. In one small trial, the odds of success at 6 months were 6 times higher with injections than with shoes and pads.
Sources 5, 2, 3, 11
Other injections and treatments: small studies onlyMixed evidence
Alcohol injections, radiofrequency treatment (heating the nerve), freezing (cryotherapy) and botulinum toxin have been studied only in case series of limited quality, and shockwave therapy did no better than a dummy treatment in one trial. In a hospital's records, 26% of people treated with radiofrequency later had surgery and 33% had it repeated. The NHS keeps steroid or alcohol injections, and surgery, for very severe symptoms or when other treatments haven't worked.
Sources 11, 14, 1
Manipulation by a therapist: one small trialEmerging evidence
In one trial of 40 people, six sessions of foot and ankle joint manipulation and mobilisation over 3 weeks eased pain more than a dummy treatment, by about 15 points on a 100-point scale, but pain was measured only at the end of treatment. An NHS trust says it has been found to help in some cases.
Sources 11, 4
Exercise: no trialsMixed evidence
No trial has tested exercise for Morton's neuroma. The calf stretching and foot strengthening on this page rest on one NHS podiatry leaflet, which suggests calf stretches, toe and forefoot massage, a foot roller and foot-muscle strengthening, and one expert review, which lists stretching of the calf and the small foot muscles and notes that tight calves are more common with pain in the front of the foot.
So treat the plan below as a sensible, low-risk way to keep the foot and calf in good order and stay active while shoes and pads do the main work, not as a proven treatment.
Sources 2, 11, 13, 3
Surgery: usually helps, but not for everyoneEmerging evidence
Removing the nerve (neurectomy) is for symptoms that persist after other treatment. A review found good or excellent results in 70 to 80%, but consistently only about half had no pain afterwards, about 30% were better with some pain left, and about 1 in 10 were worse. In 81 people followed for 15 years, results were excellent or good for 77% of feet and poor for 8%, and 72% had numbness between the toes, which didn't affect satisfaction. In another 120 people, 51% had good or excellent results and 40% poor, with worse results for the second web space.
Across 8 studies, a cut on the sole left numbness less often than one on the top of the foot (49% against 62%) but a tender scar more often (17% against 6%). An NHS trust adds that painful scars happen in about 5 in 100, and the problem comes back later in 1 in 4 of those who got better.
Sources 3, 15, 16, 17, 2, 4