What the guidelines sayStrong evidence
ESHRE recommends that clinicians discuss non-medical ways to improve quality of life, but says no recommendation can be made for any specific one, including physiotherapy and exercise, "as the potential benefits and harms are unclear". NICE's only non-drug recommendation is against traditional Chinese medicine and supplements. WHO says pain management that includes physiotherapy and CBT can help reduce pain and improve quality of life.
Sources 4, 5, 3
Reviews of exerciseMixed evidence
A 2021 review found 3 small studies (109 women) of flexibility, strength, cardio and yoga, and couldn't determine an effect. A 2025 review found 6 trials (251 women); only 2 (71 women) could be pooled, showing better quality of life scores for pain, control and emotional wellbeing.
Sources 6, 7
The largest exercise trialEmerging evidence
In one trial of 81 women in Norway with confirmed endometriosis and pelvic pain of at least 4 out of 10, everyone went on a 4-hour pain course covering exercise, relaxation and deep breathing. Half then had a weekly 60-minute supervised group session of general exercise with pelvic floor training for 4 months, plus home training 2 to 3 times a week. Their day-to-day pelvic pain eased by 1.1 points out of 10 more than in the comparison group at 4 months, and by 1.5 points at 12 months, but their worst pain didn't improve and other outcomes were unclear.
There are gaps. Women managed 1.8 sessions a week on average, and by 12 months many hadn't returned questionnaires (in the follow-up paper, 63% of the exercise group and 73% of the comparison group did), so the 1-year result is less certain. Sexual function scores were better at 4 months but not at 12, and that difference may partly reflect more sexually active women in the exercise group.
Sources 8, 22, 16
A 9-week supervised programmeEmerging evidence
In 31 women not helped by standard treatment, 9 weeks of supervised exercise (a week learning to steady the lower back and pelvis, then stretching, aerobic and strength work) improved quality of life with large effects, after the programme and at a year. Pain with sex, strength and fatigue also improved. Adherence was 90.6%, and there were no notable health problems.
Sources 9, 23
Exercise with pain educationEmerging evidence
In 40 women, 24 sessions of exercise with education about how pain works, over 8 weeks, improved quality of life more than online lifestyle advice, at 8 weeks and 3 months.
Source 24
Strength trainingEmerging evidence
In 64 women, 8 weeks of functional strength training twice a week improved grip strength, jump height, pain and quality of life, with no change in the comparison group.
Source 25
YogaMixed evidence
In 40 women, 90-minute yoga sessions twice a week for 8 weeks lowered daily pain. But in the largest trial, 334 people did 8 weekly online yoga sessions or online CBT, or read education material: yoga was no better than education for quality of life, though it improved period symptoms and pain with sex, while CBT improved quality of life and pain. 40% dropped out of the yoga and CBT groups. Studies without a comparison group were positive.
Sources 26, 10, 27, 28
Physiotherapy treatmentsEmerging evidence
In a review of 7 studies, physiotherapy treatments, mostly electrical stimulation, laser and other treatments applied to the painful area, eased pain by about 2 points out of 10. Other reviews of mixed physical therapies were positive, but the studies varied widely.
Sources 29, 30, 31
SafetyEmerging evidence
The supervised programmes reported no notable health problems, and the Norwegian trial's lead author reported no adverse effects. In the yoga and CBT trial there were 12 mild adverse events, mostly flare-ups of existing problems.
Sources 9, 16, 10
Bone on GnRH treatmentEmerging evidence
Medicines that switch off oestrogen (gonadotrophin-releasing hormone, or GnRH, medicines) cause bone loss, so ESHRE suggests add-back hormone treatment with them. In a pilot trial of 19 women, training didn't stop the early hip bone loss, but a year later trained women were 0.6% below their starting level, against 3.6% below in the comparison group.
Sources 4, 32
PreventionMixed evidence
In 9 studies, recent physical activity wasn't significantly linked with a lower risk of endometriosis. ESHRE says there's no direct evidence of benefit, but a healthy lifestyle with regular activity can be advised.
Sources 33, 4
Medicines and surgery carry the evidenceStrong evidence
NICE suggests a short trial, for example 3 months, of paracetamol or an anti-inflammatory, and offers hormonal treatment such as the combined pill or a progestogen, which "can reduce pain and has no permanent negative effect on subsequent fertility". ESHRE strongly recommends hormone treatment, and surgery as one option for pain.
Sources 5, 4